Besides strengthening independent innovation, Koreda also actively cooperates with the Chinese academy of sciences, Hefei university of technology and Anhui university and other scientific research institutions, and builds an Innovation System consisted of scientific research institutes and production enterprises; especially, we establish closely cooperative relations with Hefei university of technology, including product research and development, personnel training and project development, etc; we won the great supports form Hefei university of technology. Cooperating with chemical academy of Hefei university of technology, we have successfully developed key intermediates project of Olmesartan medoxomil, which can annually produce 500 tons of DMDO and DMDO-Cl series products.